Details for gene set KEGG_ALZHEIMERS

Table: GSEA Results Summary

Dataset	RNR_GSEA_DESEQ2_FC
Phenotype	NoPhenotypeAvailable
Upregulated in class	na_neg
GeneSet	KEGG_ALZHEIMERS_DISEASE
Enrichment Score (ES)	-0.13825227
Normalized Enrichment Score (NES)	-2.0504935
Nominal p-value	0.0042283298
FDR q-value	0.019639455
FWER p-Value	0.276

Table: GSEA details [plain text format]
	PROBE	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	CALML3	521	0.869	-0.0217	No
2	LPL	655	0.720	-0.0224	No
3	SNCA	733	0.649	-0.0201	No
4	MME	1109	0.476	-0.0339	No
5	EIF2AK3	1293	0.406	-0.0373	No
6	GRIN1	1451	0.356	-0.0393	No
7	TNF	1751	0.302	-0.0490	No
8	ITPR1	1873	0.281	-0.0490	No
9	GRIN2A	2109	0.250	-0.0553	No
10	COX8C	2156	0.244	-0.0513	No
11	ITPR2	2812	0.185	-0.0802	No
12	ERN1	2870	0.181	-0.0768	No
13	ADAM10	2877	0.180	-0.0706	No
14	RYR3	2980	0.174	-0.0697	No
15	COX6A2	3082	0.168	-0.0686	No
16	PLCB4	3285	0.156	-0.0731	No
17	APP	3540	0.143	-0.0803	No
18	GSK3B	3855	0.128	-0.0908	No
19	COX7A1	4154	0.116	-0.1005	No
20	PLCB1	4793	0.095	-0.1285	No
21	APAF1	4810	0.094	-0.1229	No
22	ATP5H	4912	0.091	-0.1219	No
23	MAPK1	5144	0.085	-0.1279	No
24	ADAM17	5184	0.084	-0.1235	No
25	CASP3	5309	0.080	-0.1237	No
26	NCSTN	5579	0.073	-0.1318	Yes
27	CACNA1S	5600	0.072	-0.1263	Yes
28	COX7C	5729	0.069	-0.1268	Yes
29	ATP5G2	5754	0.068	-0.1216	Yes
30	UQCR11	5763	0.068	-0.1155	Yes
31	COX8A	5842	0.066	-0.1133	Yes
32	ATP5O	5938	0.063	-0.1119	Yes
33	UQCRQ	6115	0.060	-0.1149	Yes
34	NDUFA4	6150	0.059	-0.1103	Yes
35	COX6C	6409	0.052	-0.1178	Yes
36	NDUFA3	6440	0.052	-0.1129	Yes
37	NDUFA1	6720	0.046	-0.1215	Yes
38	COX7B	7015	0.039	-0.1309	Yes
39	CALM3	7021	0.039	-0.1247	Yes
40	ATF6	7096	0.038	-0.1222	Yes
41	CASP9	7152	0.036	-0.1187	Yes
42	COX5B	7229	0.035	-0.1163	Yes
43	NDUFB8	7274	0.034	-0.1122	Yes
44	NDUFS8	7329	0.032	-0.1086	Yes
45	ATP5B	7366	0.032	-0.1041	Yes
46	APH1A	7379	0.031	-0.0982	Yes
47	PSEN1	7445	0.030	-0.0952	Yes
48	ATP5J	7467	0.029	-0.0899	Yes
49	FAS	7473	0.029	-0.0837	Yes
50	PPP3CB	7579	0.027	-0.0829	Yes
51	CALML6	7588	0.027	-0.0768	Yes
52	ATP5E	7602	0.027	-0.0710	Yes
53	NDUFC1	7607	0.027	-0.0647	Yes
54	HSD17B10	7680	0.025	-0.0621	Yes
55	BACE1	7687	0.025	-0.0560	Yes
56	NDUFV2	7849	0.022	-0.0582	Yes
57	NDUFA2	7942	0.020	-0.0567	Yes
58	NDUFB1	7944	0.020	-0.0502	Yes
59	MAPK3	7950	0.020	-0.0440	Yes
60	GNAQ	8139	0.017	-0.0477	Yes
61	CACNA1F	8144	0.017	-0.0414	Yes
62	NDUFC2	8260	0.014	-0.0411	Yes
63	NDUFB4	8305	0.013	-0.0370	Yes
64	COX7A2	8448	0.010	-0.0382	Yes
65	UQCRB	8463	0.010	-0.0325	Yes
66	COX4I2	8492	0.009	-0.0275	Yes
67	NDUFS1	8626	0.006	-0.0282	Yes
68	IDE	8675	0.005	-0.0243	Yes
69	COX6B1	8686	0.005	-0.0184	Yes
70	NDUFB5	8979	-0.000	-0.0277	Yes
71	COX7A2L	9011	-0.001	-0.0229	Yes
72	SDHA	9175	-0.005	-0.0252	Yes
73	CYCS	9213	-0.005	-0.0207	Yes
74	ATP5F1	9252	-0.006	-0.0163	Yes
75	NDUFV1	9298	-0.007	-0.0122	Yes
76	CALM1	9305	-0.007	-0.0060	Yes
77	UQCR10	9315	-0.007	-0.0000	Yes
78	NDUFA4L2	9327	-0.008	0.0059	Yes
79	CASP8	9444	-0.010	0.0061	Yes
80	NDUFB7	9689	-0.015	-0.0006	Yes
81	NDUFA9	9710	-0.015	0.0048	Yes
82	NDUFA10	9737	-0.016	0.0099	Yes
83	COX4I1	9807	-0.017	0.0126	Yes
84	NDUFA8	9875	-0.018	0.0155	Yes
85	PSENEN	9991	-0.020	0.0158	Yes
86	NDUFS4	10092	-0.022	0.0168	Yes
87	NDUFA6	10244	-0.025	0.0152	Yes
88	NDUFS2	10375	-0.027	0.0146	Yes
89	CALM2	10416	-0.028	0.0190	Yes
90	ATP5A1	10428	-0.028	0.0249	Yes
91	NDUFS7	10561	-0.031	0.0242	Yes
92	SDHB	10586	-0.032	0.0294	Yes
93	ATP5G3	10711	-0.034	0.0292	Yes
94	NDUFA5	10719	-0.034	0.0353	Yes
95	NDUFB2	10753	-0.035	0.0400	Yes
96	PLCB3	10761	-0.035	0.0461	Yes
97	UQCRFS1	10764	-0.035	0.0525	Yes
98	SDHC	10904	-0.039	0.0515	Yes
99	NDUFV3	11017	-0.042	0.0519	Yes
100	PPP3CC	11035	-0.042	0.0575	Yes
101	UQCRC1	11054	-0.043	0.0630	Yes
102	NDUFS6	11113	-0.044	0.0664	Yes
103	NDUFB3	11120	-0.044	0.0725	Yes
104	UQCRH	11225	-0.047	0.0734	Yes
105	NDUFB9	11314	-0.049	0.0751	Yes
106	NDUFB6	11629	-0.056	0.0646	Yes
107	UQCRC2	11688	-0.058	0.0680	Yes
108	ATP5D	11716	-0.059	0.0730	Yes
109	CYC1	11720	-0.059	0.0793	Yes
110	CAPN1	11734	-0.059	0.0851	Yes
111	ATP5C1	11773	-0.060	0.0896	Yes
112	NDUFS3	12118	-0.068	0.0774	Yes
113	GAPDH	12248	-0.071	0.0769	Yes
114	NDUFS5	12413	-0.075	0.0746	Yes
115	COX6A1	12438	-0.076	0.0798	Yes
116	NAE1	12534	-0.078	0.0811	Yes
117	ATP5G1	12712	-0.084	0.0780	Yes
118	CAPN2	12717	-0.084	0.0843	Yes
119	PPP3R1	12989	-0.092	0.0761	Yes
120	BACE2	13072	-0.094	0.0782	Yes
121	CACNA1C	13282	-0.101	0.0734	Yes
122	COX5A	13501	-0.108	0.0681	Yes
123	MAPT	13599	-0.112	0.0693	Yes
124	CASP7	13630	-0.113	0.0742	Yes
125	NDUFB10	13693	-0.115	0.0773	Yes
126	ITPR3	13705	-0.116	0.0832	Yes
127	APBB1	14191	-0.138	0.0635	Yes
128	ATP2A3	14270	-0.143	0.0657	Yes
129	NDUFAB1	14361	-0.147	0.0674	Yes
130	CACNA1D	14368	-0.147	0.0735	Yes
131	FADD	14416	-0.150	0.0775	Yes
132	CDK5	14428	-0.150	0.0834	Yes
133	PPP3CA	14461	-0.152	0.0881	Yes
134	LRP1	14566	-0.157	0.0890	Yes
135	GRIN2D	14720	-0.165	0.0872	Yes
136	NDUFA7	14804	-0.172	0.0892	Yes
137	COX6B2	14837	-0.174	0.0940	Yes
138	ATP2A1	14977	-0.183	0.0929	Yes
139	BAD	15014	-0.187	0.0975	Yes
140	ATP2A2	15016	-0.187	0.1039	Yes
141	BID	15088	-0.192	0.1066	Yes
142	PSEN2	15126	-0.195	0.1111	Yes
143	TNFRSF1A	15755	-0.257	0.0836	Yes
144	PLCB2	16031	-0.291	0.0752	Yes
145	CDK5R1	16109	-0.301	0.0775	Yes
146	GRIN2C	16250	-0.326	0.0764	Yes
147	APOE	17052	-0.519	0.0396	Yes
148	NOS1	17389	-0.675	0.0279	Yes
149	PPP3R2	17775	-0.944	0.0135	Yes
150	CHP2	18039	-1.173	0.0058	Yes
151	GRIN2B	18050	-1.185	0.0117	Yes
152	IL1B	18055	-1.190	0.0180	Yes
153	COX7B2	18504	-2.743	0.0003	Yes
154	SDHD	18603	-8.297	0.0015	Yes